Study on synergic effect of phytomolecular compounds in terms of anti-amylase activity


Abstract:
Drugs play an essential role in the treatment and prevention of various diseases. The drug derived from the phytocompounds has an impact on a wide variety of ailments. The beneficial effects of plant sources are due to the nature of phytomolecules which serve to heal the human systems. Understanding the interaction of drug-drug compounds has a vital role to increase the overall therapeutic effects and maintain the homeostatic conditions of the system. The plant active compounds with similar activity from different origins and in combinations have been found to enhance the overall activity in synergy. These effects have been used to treat various diseases and disorders. In this research, an essential approach to understand the anti-amylase activity of garlic and ginger extracts, the extracts were analysed individually and in combination as ginger-garlic complex. The synergistic effects on anti-amylase using phytomolecular extractions, analysis of starch concentration, analysis of reducing sugar and FTIR analysis were performed. The results have shown consistency in inhibiting the alpha-amylase activity individually and in combinations. Significant reductions in the starch concentrations of ginger-garlic extract were observed. The study proves that the synergic effect of ginger and garlic extracts has effects on inhibition of alpha-amylase. The outcome of the study indicates the need for future analysis to understand the mechanism of action between the components of ginger-garlic complex. These findings could serve as an important pathway to treat the diabetic disorder effectively.

Keywords:
Anti-amylase, Phytochemicals, Garlic, Ginger, Synergism

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How to cite this article:
Akshay B, Selvakumar K, Geetha M & Madhan R. Study on synergic effect of phytomolecular compounds in terms of anti-amylase activity. Journal of Biological and Information Sciences. 2016. 5 (1). 1-5.
Available from: http://www.biolim.com/journals/BOJ001/001/BOJ001A0032.